Gene
cyt1
- ID
- ZDB-GENE-991008-6
- Name
- type I cytokeratin, enveloping layer
- Symbol
- cyt1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to enable structural molecule activity. Acts upstream of or within cell migration involved in gastrulation. Predicted to be located in intermediate filament. Is expressed in EVL; embryonic structure; epidermis; epithelium; and periderm. Human ortholog(s) of this gene implicated in several diseases, including corneal dystrophy (multiple); ectodermal dysplasia (multiple); epidermolytic hyperkeratosis; focal nonepidermolytic palmoplantar keratoderma 1; and hereditary mucosal leukokeratosis. Orthologous to several human genes including KRT13 (keratin 13); KRT14 (keratin 14); and KRT15 (keratin 15).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 21 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Pei et al., 2007
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Intermediate filament, rod domain | Keratin, type I |
|---|---|---|---|
|
UniProtKB:Q9PWD8
|
429 |
Interactions and Pathways
No data available
Plasmids
No data available