Gene
cyt1
- ID
- ZDB-GENE-991008-6
- Name
- type I cytokeratin, enveloping layer
- Symbol
- cyt1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to enable structural molecule activity. Acts upstream of or within cell migration involved in gastrulation. Predicted to be located in intermediate filament. Predicted to be active in cytoskeleton. Is expressed in EVL; embryonic structure; epidermis; epithelium; and periderm. Human ortholog(s) of this gene implicated in several diseases, including corneal dystrophy (multiple); ectodermal dysplasia (multiple); epidermolytic hyperkeratosis (multiple); focal nonepidermolytic palmoplantar keratoderma 1; and pachyonychia congenita. Orthologous to several human genes including KRT13 (keratin 13); KRT14 (keratin 14); and KRT15 (keratin 15).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 21 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Pei et al., 2007
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Intermediate filament, rod domain | Keratin, type I |
|---|---|---|---|
|
UniProtKB:Q9PWD8
|
429 |
Interactions and Pathways
No data available
Plasmids
No data available