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ZIRC
ZFIN ID: ZDB-GENE-990415-127
Gene Name: SIX homeobox 3a
Gene Symbol: six3a
Sequence Ontology ID : SO:0001217

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Previous Names: six3.1, six3 (1), etID309945.13 (1), etID46760.13 (1), wu:fa01b08, wu:fc10a08 (1)

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(Including Attributions)
Location: Chr: 13 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and transcription regulatory region sequence-specific DNA binding activity. Involved in brain development and  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa42147 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • vu129 Point Mutation Unknown Unknown ENU
    Targeting reagents:
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH six3a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    holoprosencephaly 2 Holoprosencephaly 2 157170
    Schizencephaly 269160
    DISEASE ASSOCIATED WITH six3a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process optic nerve development (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 12)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA six3a-201 (1) 1889
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM six3a
    MARKER RELATIONSHIPS
    six3a Contained in: [BAC] DKEY-103L3 (1) (order this)
    six3a Encodes: [EST] fc10a08 (1)
    [cDNA] MGC:73025 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131362 (1) 1914 bp
    Genomic GenBank:BX537274 (1) 151298 bp
    Select Tool
    Polypeptide UniProtKB:O73708 (1) 294 aa
    Sequence Clusters UniGene:616 (1)
    Sequence Information (all 15)
    ORTHOLOGY for six3a ( Chr: 13 )
    CITATIONS (91)