Gene
isl2a
- ID
- ZDB-GENE-980526-562
- Name
- ISL LIM homeobox 2a
- Symbol
- isl2a Nomenclature History
- Previous Names
-
- isl2
- zfIsl-2
- wu:fc29g02
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in blood vessel morphogenesis; exocrine pancreas development; and neuron differentiation. Predicted to localize to nucleus. Is expressed in several structures, including ectoderm; gut; liver and biliary system; nervous system; and neural tube. Orthologous to human ISL2 (ISL LIM homeobox 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 90 figures from 60 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu308 (17 images)
Wild Type Expression Summary
- All Phenotype Data
- 15 figures from 5 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Homeobox, conserved site | Homeobox domain | Homeobox-like domain superfamily | Zinc finger, LIM-type |
|---|---|---|---|---|---|
|
UniProtKB:B3DH43
|
359 | ||||
|
UniProtKB:P53406
|
359 |
- Genome Browsers
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-isl | monoclonal | IgG1 | Mouse |
|
Developmental Studies Hybridoma Bank
|
26 | |
| Ab2-isl | monoclonal | IgG2b | Mouse |
|
Developmental Studies Hybridoma Bank
|
130 |
Plasmids
No data available