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Gene

her3

ID
ZDB-GENE-980526-204
Name
hairy-related 3
Symbol
her3 Nomenclature History
Previous Names
  • sb:eu263
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Enables DNA binding activity. Acts upstream of or within negative regulation of neurogenesis and negative regulation of transcription, DNA-templated. Predicted to be active in nucleus. Is expressed in several structures, including DEL; central nervous system; epiblast; midbrain neural keel; and neural plate. Orthologous to human HES3 (hes family bHLH transcription factor 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
19 figures from 9 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Webb et al., 2011
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With her3 Human Ortholog
No data available
Associated With her3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003650 Orange domain
Domain IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
Homologous_superfamily IPR036638 Helix-loop-helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Helix-loop-helix DNA-binding domain superfamily Myc-type, basic helix-loop-helix (bHLH) domain Orange domain
UniProtKB:F1RDU0 253
UniProtKB:Q90465 229
UniProtKB:Q568C3 253
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations