Gene
asap1b
- ID
- ZDB-GENE-091112-16
- Name
- ArfGAP with SH3 domain, ankyrin repeat and PH domain 1b
- Symbol
- asap1b Nomenclature History
- Previous Names
-
- asap1
- si:dkey-37o8.2
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to enable GTPase activator activity. Acts upstream of or within defense response to bacterium and positive regulation of macrophage migration. Predicted to be located in cytoplasm. Is expressed in head. Orthologous to human ASAP1 (ArfGAP with SH3 domain, ankyrin repeat and PH domain 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Cui et al., 2020
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | AH/BAR domain superfamily | Ankyrin repeat | Ankyrin repeat-containing domain superfamily | ArfGAP domain superfamily | ARFGAP/RecO-like zinc finger | Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein | Arf GTPase activating protein | ASAP1, BAR domain | ASAP1, SH3 domain | ASAP, PH domain | BAR domain | PH-like domain superfamily | Pleckstrin homology domain | SH3 domain | SH3-like domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A2R8RMX4 | InterPro | 1062 | |||||||||||||||
| UniProtKB:A0A8M3ANG5 | InterPro | 1133 | |||||||||||||||
| UniProtKB:A0A8M3AZ08 | InterPro | 1137 | |||||||||||||||
| UniProtKB:A0A8M3AVY1 | InterPro | 1136 | |||||||||||||||
| UniProtKB:A0A8M2B9F9 | InterPro | 1086 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
asap1b-201
(1)
|
Ensembl | 8,967 nt | ||
| mRNA |
asap1b-202
(1)
|
Ensembl | 1,048 nt | ||
| mRNA |
asap1b-204
(1)
|
Ensembl | 669 nt | ||
| mRNA |
asap1b-205
(1)
|
Ensembl | 4,009 nt | ||
| mRNA |
asap1b-206
(1)
|
Ensembl | 8,508 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-37O8 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_005162605 (1) | 5138 nt | ||
| Genomic | GenBank:AL840641 (1) | 177428 nt | ||
| Polypeptide | UniProtKB:A0A8M3AZ08 (1) | 1137 aa |
- Cui, J., Chen, G., Wen, D., Wang, Y., Zhao, Z., Wu, C. (2020) Asap1 Affects the Susceptibility of Zebrafish to Mycobacterium by Regulating Macrophage Migration. Frontiers in cellular and infection microbiology. 10:519503
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Ningappa, M., So, J., Glessner, J., Ashokkumar, C., Ranganathan, S., Min, J., Higgs, B.W., Sun, Q., Haberman, K., Schmitt, L., Vilarinho, S., Mistry, P.K., Vockley, G., Dhawan, A., Gittes, G.K., Hakonarson, H., Jaffe, R., Subramaniam, S., Shin, D., Sindhi, R. (2015) The Role of ARF6 in Biliary Atresia. PLoS One. 10:e0138381
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