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ZIRC
ZFIN ID: ZDB-GENE-060612-1
Gene Name: crumbs cell polarity complex component 2a
Gene Symbol: crb2a
Sequence Ontology ID : SO:0000704

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Previous Names: crb2 (1), oko meduzy, ome

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(Including Attributions)
Location: Chr: 21 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have calcium ion binding activity. Involved in several processes, including apical protein localization; embryonic retina morphogenesis in camera-type eye; and heterophilic cell-cell  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la022098Tg Transgenic Insertion Unknown Unknown DNA
m98 Point Mutation Unknown Premature Stop ENU
m289 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • m298 Unknown Unknown Unknown ENU
    m320 Unknown Unknown Unknown ENU
    rw267 Unknown Unknown Unknown
    rw407 Unknown Unknown Unknown
    s256 Unknown Unknown Unknown ENU
    sa12901 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18328 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa32334 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    DISEASE ASSOCIATED WITH crb2a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    focal segmental glomerulosclerosis 9 Focal segmental glomerulosclerosis 9 616220
    Ventriculomegaly with cystic kidney disease 219730
    DISEASE ASSOCIATED WITH crb2a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell-cell adhesion (more)
    Cellular Component plasma membrane (more)
    Molecular Function calcium ion binding (more)
    GO Terms (all 15)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA crb2a-201 (1) 5153
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIES
    PLASMIDSNo data available
    MARKER RELATIONSHIPS
    crb2aContained in: [Fosmid] CH1073-90E4 (1) (order this), CH1073-314H16 (1) (order this)
    crb2aEncodes: [cDNA] MGC:193515 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001045299 (1) 5153bp
    Genomic GenBank:CU855942 (1) 40595bp
    Select Tool
    Polypeptide UniProtKB:B3DGM6 (1) 1466aa
    Sequence Clusters UniGene:139497 (1)
    Sequence Information (all 16)
    ORTHOLOGY for crb2a (Chr: 21)
    CITATIONS (62)