ZFIN is now using GRCz12tu for Genomic Data
Gene
popdc2
- ID
- ZDB-GENE-060518-2
- Name
- popeye domain cAMP effector 2
- Symbol
- popdc2 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable cAMP binding activity. Acts upstream of or within cardiac conduction; heart looping; and striated muscle cell differentiation. Predicted to be located in plasma membrane. Predicted to be active in sarcolemma. Is expressed in heart rudiment; musculature system; pectoral fin bud; pericardial region; and somite. Orthologous to human POPDC2 (popeye domain cAMP effector 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 9 figures from Kirchmaier et al., 2012
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Cardiac conduction disease with or without cardiomyopathy 2 | 621367 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Cyclic nucleotide-binding domain superfamily | POPDC1-3 | POPDC1-3 domain |
|---|---|---|---|---|---|
| UniProtKB:A9JT76 | InterPro | 367 | |||
| UniProtKB:Q6JWV8 | InterPro | 370 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
pla1a-203
(1)
|
Ensembl | 6,568 nt | ||
| mRNA |
popdc2-201
(1)
|
Ensembl | 2,645 nt | ||
| mRNA |
popdc2-202
(1)
|
Ensembl | 2,476 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-popdc2 | polyclonal | Rabbit |
|
Sigma-Aldrich
|
2 |
Plasmids
No data available
- Genome Browsers