Gene
il4r.1
- ID
- ZDB-GENE-050227-5
- Name
- interleukin 4 receptor, tandem duplicate 1
- Symbol
- il4r.1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Exhibits interleukin-4 binding activity. Involved in neurogenesis and regeneration. Localizes to plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including acne; allergic conjunctivitis; human immunodeficiency virus infectious disease; multiple sclerosis (multiple); and renal tuberculosis. Is expressed in several structures, including digestive system; gill; immune system; integument; and ovary. Orthologous to human IL4R (interleukin 4 receptor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:113063 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Fibronectin type III superfamily | Immunoglobulin-like fold | Interleukin-4 receptor alpha, N-terminal |
|---|---|---|---|---|
|
UniProtKB:B2BJ88
|
368 | |||
|
UniProtKB:F1QH70
|
624 | |||
|
UniProtKB:A8WHA2
|
421 | |||
|
UniProtKB:B2BJ89
|
220 | |||
|
UniProtKB:A0A8M2BBP4
|
623 | |||
|
UniProtKB:Q5EAS6
|
220 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
il4r.1-201
(1)
|
Ensembl | 1,854 nt | ||
| mRNA |
il4r.1-202
(1)
|
Ensembl | 2,062 nt | ||
| mRNA |
il4r.1-203
(1)
|
Ensembl | 1,250 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-il4r.1 | IgM | Rabbit |
|
1 | |||
| Ab2-il4r.1 | Mouse |
|
1 |
Plasmids
No data available