Gene
dvl2
- ID
- ZDB-GENE-041118-20
- Name
- dishevelled segment polarity protein 2
- Symbol
- dvl2 Nomenclature History
- Previous Names
-
- sb:eu471
- wu:fc05d12
- wu:fo71e09
- wu:fp54a02
- zgc:55372
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have frizzled binding activity. Involved in several processes, including cell migration in hindbrain; convergent extension involved in axis elongation; and post-anal tail morphogenesis. Localizes to cell cortex and spindle. Is expressed in liver. Orthologous to human DVL2 (dishevelled segment polarity protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000591 | DEP domain |
| Domain | IPR001158 | DIX domain |
| Domain | IPR001478 | PDZ domain |
| Domain | IPR003351 | Dishevelled protein domain |
| Domain | IPR024580 | Dishevelled C-terminal |
| Family | IPR008339 | Dishevelled family |
| Family | IPR015506 | Dishevelled-related protein |
| Homologous_superfamily | IPR029071 | Ubiquitin-like domain superfamily |
| Homologous_superfamily | IPR036034 | PDZ superfamily |
| Homologous_superfamily | IPR036388 | Winged helix-like DNA-binding domain superfamily |
| Homologous_superfamily | IPR036390 | Winged helix DNA-binding domain superfamily |
| Homologous_superfamily | IPR038207 | DIX domain superfamily |
Domain Details Per Protein
| Protein | Length | DEP domain | Dishevelled C-terminal | Dishevelled family | Dishevelled protein domain | Dishevelled-related protein | DIX domain | DIX domain superfamily | PDZ domain | PDZ superfamily | Ubiquitin-like domain superfamily | Winged helix DNA-binding domain superfamily | Winged helix-like DNA-binding domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q803Q5
|
747 |
Interactions and Pathways
No data available
Plasmids