Gene

dvl2

ID
ZDB-GENE-041118-20
Name
dishevelled segment polarity protein 2
Symbol
dvl2 Nomenclature History
Previous Names
  • sb:eu471
  • wu:fc05d12
  • wu:fo71e09
  • wu:fp54a02
  • zgc:55372
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have frizzled binding activity. Involved in several processes, including cell migration in hindbrain; convergent extension involved in axis elongation; and post-anal tail morphogenesis. Localizes to cell cortex and spindle. Is expressed in liver. Orthologous to human DVL2 (dishevelled segment polarity protein 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
7 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dvl2 Human Ortholog
No data available
Associated With dvl2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000591 DEP domain
Domain IPR001158 DIX domain
Domain IPR001478 PDZ domain
Domain IPR003351 Dishevelled protein domain
Domain IPR024580 Dishevelled C-terminal
Family IPR008339 Dishevelled family
Family IPR008341 Dishevelled-2
Family IPR015506 Dishevelled-related protein
Homologous_superfamily IPR029071 Ubiquitin-like domain superfamily
Homologous_superfamily IPR036034 PDZ superfamily
Homologous_superfamily IPR036388 Winged helix-like DNA-binding domain superfamily
Homologous_superfamily IPR036390 Winged helix DNA-binding domain superfamily
Homologous_superfamily IPR038207 DIX domain superfamily
Domain Details Per Protein
Protein Length DEP domain Dishevelled-2 Dishevelled C-terminal Dishevelled family Dishevelled protein domain Dishevelled-related protein DIX domain DIX domain superfamily PDZ domain PDZ superfamily Ubiquitin-like domain superfamily Winged helix DNA-binding domain superfamily Winged helix-like DNA-binding domain superfamily
UniProtKB:F1QM97 747
UniProtKB:Q803Q5 747
UniProtKB:Q673F1 747
Transcripts
Genome Browsers
Interactions and Pathways
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-dvl2 polyclonal Rabbit
1
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations