Gene

mia3

ID
ZDB-GENE-041014-270
Name
MIA SH3 domain ER export factor 3
Symbol
mia3 Nomenclature History
Previous Names
  • mia2
  • sb:eu1084
  • si:ch211-180b22.1
  • si:ch211-180b22.2
  • wu:fb05c09
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Involved in endoplasmic reticulum to Golgi vesicle-mediated transport; protein secretion; and vesicle cargo loading. Is expressed in liver; median fin fold; and musculature system. Orthologous to human MIA3 (MIA SH3 domain ER export factor 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from Thisse et al., 2005
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mia3 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
?Ondontochondrodysplasia 2 with hearing loss and diabetes 619269
Associated With mia3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001452 SH3 domain
Homologous_superfamily IPR036028 SH3-like domain superfamily
Domain Details Per Protein
Protein Length SH3 domain SH3-like domain superfamily
UniProtKB:F1R5N2 1874
UniProtKB:Q5SP05 786
UniProtKB:A0A0R4IGM8 1852
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Note
Woods, et al. (2005. Genome Res. 15:1307-1314.) report the 5' portion of this gene as mia2 and assigned orthology to human MIA2 based on amino acid identity. Subsequent analysis suggests their sequence is part of mia3. The mia2 gene is found on chromosome 17 with orthology to human MIA2 and mouse Mia2 based on amino acid identity and conserved synteny.
Citations