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ZIRC
ZFIN ID: ZDB-GENE-040912-91
Gene Name: cytochrome c oxidase copper chaperone COX17
Gene Symbol: cox17    Nomenclature History

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Previous Names: zgc:103765, zgc:191605

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have copper chaperone activity. Involved in response to copper ion. Predicted to localize to the mitochondrial intermembrane space. Is expressed in several structures, including blood; lens; liver; musculature system; and solid lens vesicle. Orthologous to human COX17 (cytochrome c oxidase copper chaperone COX17).
Genome Resources: Alliance (1),  Gene:447914 (1),  Ensembl(GRCz11):ENSDARG00000069920 (1)
GENE EXPRESSION
All Expression Data: 15 figures from 2 publications
Directly Submitted Expression Data: 6 figures (19 images) from Thisse et al., 2004 [MGC:103765]
  6 figures (8 images) from Thisse et al., 2004 [IMAGE:7158049]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hza2 Insertion Unknown Unknown CRISPR
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
CRISPR1-cox17 1
PHENOTYPE No data available
DISEASE ASSOCIATED WITH cox17 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH cox17 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process response to copper ion (more)
Cellular Component mitochondrial intermembrane space (more)
Molecular Function copper chaperone activity (more)
GO Terms (all 6)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR007745 (1)
  • InterPro:IPR009069 (1)
  • Pfam:PF05051 (1)
  • TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cox17-201 (1)    Ensembl 497
    cox17-202 (1)    Ensembl 654
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cox17 No data available
    MARKER RELATIONSHIPS
    cox17 Contained in: [BAC] RP71-68N21 (1) (order this)
    cox17 Encodes: [EST] IMAGE:7158049 (1) (order this)
    [cDNA] MGC:103765 (1) (order this), MGC:191605 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001004652 (1) 519 bp
    Genomic GenBank:BX511129 (1) 152922 bp
    Select Tool
    Polypeptide UniProtKB:Q66I53 (1) 68 aa
    Sequence Clusters UniGene:82168 (1)
    Sequence Information (all 16)
    ORTHOLOGY for cox17 ( Chr: 9 )
    CITATIONS (20)