Gene

sf3b1

ID
ZDB-GENE-040827-3
Name
splicing factor 3b, subunit 1
Symbol
sf3b1 Nomenclature History
Previous Names
  • tst
  • wu:fb99f09
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to have mRNA binding activity. Involved in several processes, including hemopoiesis; melanocyte differentiation; and neural crest cell development. Predicted to localize to U2 snRNP and spliceosomal complex. Is expressed in brain; neural tube; and trunk. Human ortholog(s) of this gene implicated in myelodysplastic syndrome. Orthologous to human SF3B1 (splicing factor 3b subunit 1).
Genome Resources
Note
None
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
20 figures from 6 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sf3b1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
myelodysplastic syndrome Alliance Myelodysplastic syndrome, somatic 614286
Associated With sf3b1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR015016 Splicing factor 3B subunit 1
Family IPR038737 Splicing factor 3B subunit 1-like
Homologous_superfamily IPR011989 Armadillo-like helical
Homologous_superfamily IPR016024 Armadillo-type fold
Domain Details Per Protein
Protein Length Armadillo-like helical Armadillo-type fold Splicing factor 3B subunit 1 Splicing factor 3B subunit 1-like
UniProtKB:F1QQZ1 1315
UniProtKB:Q6DRD6 965
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations