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ZIRC
ZFIN ID: ZDB-GENE-040801-111
Gene Name: suppressor of variegation 3-9 homolog 1a
Gene Symbol: suv39h1a    Nomenclature History

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Previous Names: suv39h1, fe02c04, wu:fe02c04, zgc:101027

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Predicted to have histone methyltransferase activity (H3-K9 specific). Involved in exocrine pancreas development; histone H3-K9 methylation; and retina morphogenesis in camera-type eye. Predicted to localize to the nucleus. Is expressed in several structures, including blastomere; digestive system; head; integument; and trunk musculature. Orthologous to several human genes including SUV39H1 (suppressor of variegation 3-9 homolog 1).
Genome Resources: Alliance (1),  Gene:445198 (1),  Ensembl(GRCz11):ENSDARG00000026799 (1)
GENE EXPRESSION
All Expression Data: 4 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:6908410]
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa16242 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44685 Point Mutation Unknown Unknown ENU
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-suv39h1a
    1
    CRISPR2-suv39h1a
    1
    MO1-suv39h1a N/A 3
    MO2-suv39h1a N/A 1
    DISEASE ASSOCIATED WITH suv39h1a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH suv39h1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process exocrine pancreas development (more)
    Cellular Component chromosome (more)
    Molecular Function histone-lysine N-methyltransferase activity (more)
    GO Terms (all 17)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA suv39h1a-201 (1)    Ensembl 1456
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM suv39h1a No data available
    MARKER RELATIONSHIPS
    suv39h1a Contained in: [BAC] DKEY-16N15 (1) (order this)
    suv39h1a Encodes: [EST] fe02c04, IMAGE:6908410 (1) (order this)
    [cDNA] MGC:101027 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001003592 (1) 1414 bp
    Genomic GenBank:BX005340 (1) 119181 bp
    Select Tool
    Polypeptide UniProtKB:Q6DGD3 (1) 411 aa
    Sequence Clusters UniGene:80633 (1)
    Sequence Information (all 17)
    ORTHOLOGY for suv39h1a ( Chr: 8 )
    CITATIONS (26)