suv39h1a

ID

ZDB-GENE-040801-111

Name

SUV39H1 histone lysine methyltransferase a

Symbol

suv39h1a Nomenclature History

Previous Names

suv39h1
fe02c04
wu:fe02c04
zgc:101027

Type

protein_coding_gene

Location

Chr: 8 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Enables histone H3K9 methyltransferase activity. Acts upstream of or within exocrine pancreas development and retina morphogenesis in camera-type eye. Predicted to be located in chromosome, centromeric region. Predicted to be active in nucleus. Is expressed in several structures, including blastomere; digestive system; head; integument; and trunk musculature. Orthologous to human SUV39H1 (SUV39H1 histone lysine methyltransferase).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 4 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:6908410 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With suv39h1a Human Ortholog

No data available

Associated With suv39h1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR023779	Chromo domain, conserved site
Domain	IPR000953	Chromo/chromo shadow domain
Domain	IPR001214	SET domain
Domain	IPR003616	Post-SET domain
Domain	IPR007728	Pre-SET domain
Domain	IPR023780	Chromo domain
Family	IPR011381	Histone-lysine N-methyltransferase SUV39H1/2-like
Family	IPR050973	Histone-lysine N-methyltransferase, H3 Lys-9 specific
Homologous_superfamily	IPR016197	Chromo-like domain superfamily
Homologous_superfamily	IPR046341	SET domain superfamily