Gene

havcr1

ID
ZDB-GENE-040718-131
Name
hepatitis A virus cellular receptor 1
Symbol
havcr1 Nomenclature History
Previous Names
  • DrTIM-4 (1)
  • kim1 (1)
  • kim4 (1)
  • TIM-1 (1)
  • Tim-4 (1)
  • timd1 (1)
  • wu:fb01b10 (1)
  • zgc:92647 (1)
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Involved in cytoskeletal rearrangement involved in phagocytosis, engulfment and engulfment of apoptotic cell. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in atopic dermatitis. Is expressed in macrophage. Orthologous to human HAVCR1 (hepatitis A virus cellular receptor 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
9 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Kuil et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With havcr1 Human Ortholog
No data available
Associated With havcr1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003599 Immunoglobulin subtype
Domain IPR007110 Immunoglobulin-like domain
Domain IPR013106 Immunoglobulin V-set domain
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
Domain Details Per Protein
Protein Length Immunoglobulin-like domain Immunoglobulin-like domain superfamily Immunoglobulin-like fold Immunoglobulin subtype Immunoglobulin V-set domain
UniProtKB:Q6DH50 264
UniProtKB:A0A1C6ZYS3 295
UniProtKB:E9QEV2 293
UniProtKB:A0A2R8QGQ2 324
UniProtKB:F1QLX9 280
UniProtKB:A0A1C6ZYS5 165
UniProtKB:E9QGJ4 291
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-havcr monoclonal IgG2b Rat
  • IHC
Novus Biologicals, LLC
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations