Gene

creld2

ID

ZDB-GENE-040426-1626

Name

cysteine-rich with EGF-like domains 2

Symbol

creld2 Nomenclature History

Previous Names

zgc:66383 (1)

Type

protein_coding_gene

Location

Chr: 4 Mapping Details/Browsers

Description

Predicted to have calcium ion binding activity. Predicted to localize to endoplasmic reticulum and extracellular region. Is expressed in several structures, including alar plate midbrain region; digestive system; intestinal bulb primordium; optic tectum; and yolk syncytial layer. Orthologous to human CRELD2 (cysteine rich with EGF like domains 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:66383 (13 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With creld2 Human Ortholog

No data available

Associated With creld2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018097	EGF-like calcium-binding, conserved site
Domain	IPR000742	EGF-like domain
Domain	IPR001881	EGF-like calcium-binding domain
Domain	IPR002049	Laminin-type EGF domain
Domain	IPR021852	Domain of unknown function DUF3456
Domain	IPR049883	NOTCH1 EGF-like calcium-binding domain
Family	IPR051146	Phosphatidylserine Receptors and Protein Disulfide Isomerases
Homologous_superfamily	IPR009030	Growth factor receptor cysteine-rich domain superfamily
Repeat	IPR006212	Furin-like repeat