Gene

hsc70

ID
ZDB-GENE-040426-1221
Name
heat shock cognate 70
Symbol
hsc70 Nomenclature History
Previous Names
  • zgc:63663
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Predicted to have several functions, including ATP binding activity; misfolded protein binding activity; and protein folding chaperone. Predicted to be involved in several processes, including cellular response to unfolded protein; chaperone cofactor-dependent protein refolding; and protein refolding. Predicted to localize to cytosol; nucleus; and plasma membrane. Is expressed in myotome. Orthologous to human HSPA2 (heat shock protein family A (Hsp70) member 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hsc70 Human Ortholog
No data available
Associated With hsc70 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018181 Heat shock protein 70, conserved site
Family IPR013126 Heat shock protein 70 family
Homologous_superfamily IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily
Homologous_superfamily IPR029048 Heat shock protein 70kD, C-terminal domain superfamily
Homologous_superfamily IPR043129 ATPase, nucleotide binding domain
Domain Details Per Protein
Protein Length ATPase, nucleotide binding domain Heat shock protein 70, conserved site Heat shock protein 70 family Heat shock protein 70kD, C-terminal domain superfamily Heat shock protein 70kD, peptide-binding domain superfamily
UniProtKB:Q6PGX4 647
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA hsc70-201 (1) Ensembl 2,469 nt
mRNA hsc70-202 (1) Ensembl 3,676 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations