Gene
hsc70
- ID
- ZDB-GENE-040426-1221
- Name
- heat shock cognate 70
- Symbol
- hsc70 Nomenclature History
- Previous Names
-
- zgc:63663
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to have several functions, including ATP binding activity; misfolded protein binding activity; and protein folding chaperone. Predicted to be involved in several processes, including cellular response to unfolded protein; chaperone cofactor-dependent protein refolding; and protein refolding. Predicted to localize to cytosol; nucleus; and plasma membrane. Is expressed in myotome. Orthologous to human HSPA2 (heat shock protein family A (Hsp70) member 2).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:63663 (4 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR018181 | Heat shock protein 70, conserved site |
Family | IPR013126 | Heat shock protein 70 family |
Homologous_superfamily | IPR029047 | Heat shock protein 70kD, peptide-binding domain superfamily |
Homologous_superfamily | IPR029048 | Heat shock protein 70kD, C-terminal domain superfamily |
Homologous_superfamily | IPR043129 | ATPase, nucleotide binding domain |
Domain Details Per Protein
Protein | Length | ATPase, nucleotide binding domain | Heat shock protein 70, conserved site | Heat shock protein 70 family | Heat shock protein 70kD, C-terminal domain superfamily | Heat shock protein 70kD, peptide-binding domain superfamily |
---|---|---|---|---|---|---|
UniProtKB:Q6PGX4
|
647 |
Interactions and Pathways
No data available
Plasmids
No data available