Gene

celf2

ID

ZDB-GENE-030826-35

Name

cugbp, Elav-like family member 2

Symbol

celf2 Nomenclature History

Previous Names

cb906 (1)
cugbp2
Etr-3 (1)
fj87b07
napor (1)
wu:fj87b07 (1)

Type

protein_coding_gene

Location

Chr: 4 Mapping Details/Browsers

Description

Predicted to enable mRNA 3'-UTR binding activity. Predicted to be involved in mRNA splice site recognition and regulation of alternative mRNA splicing, via spliceosome. Predicted to act upstream of or within mRNA processing. Predicted to be part of ribonucleoprotein complex. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including adaxial cell; immature eye; musculature system; nervous system; and neural plate. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 97. Orthologous to human CELF2 (CUGBP Elav-like family member 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

10 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cb906 (14 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With celf2 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
developmental and epileptic encephalopathy 97	Alliance	Developmental and epileptic encephalopathy 97	619561

Associated With celf2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000504	RNA recognition motif domain
Domain	IPR034196	CELF1/2, RNA recognition motif 1
Domain	IPR034198	CELF1/2, RNA recognition motif 2
Domain	IPR034199	CELF1/2, RNA recognition motif 3
Family	IPR002343	Paraneoplastic encephalomyelitis antigen
Homologous_superfamily	IPR012677	Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily	IPR035979	RNA-binding domain superfamily

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A8M9Q097	InterPro	502
UniProtKB:A0A8M9QB14	InterPro	497
UniProtKB:A0A8M9Q087	InterPro	547
UniProtKB:A0A8M9QB04	InterPro	544
UniProtKB:A0A8M9PH22	InterPro	518
UniProtKB:A0A8M9PU80	InterPro	537
UniProtKB:A0A8M9Q5S6	InterPro	542
UniProtKB:A0A8M9PH27	InterPro	558
UniProtKB:Q6P0B1	InterPro	514
UniProtKB:A0A8M9Q5T1	InterPro	496
UniProtKB:A0A8M9PU91	InterPro	493
UniProtKB:A0A8M9PH20	InterPro	538
UniProtKB:A0A8M9QB19	InterPro	483
UniProtKB:A0A8M9Q0A2	InterPro	492
UniProtKB:A0A8M9PH30	InterPro	544
UniProtKB:A0A8M9PU94	InterPro	477
UniProtKB:A0A8M9Q5S8	InterPro	522
UniProtKB:A0A8M9Q5T3	InterPro	482
UniProtKB:Q4U0V5	InterPro	493
UniProtKB:A0A8M9Q092	InterPro	528
UniProtKB:A0A8M9PU86	InterPro	503
UniProtKB:A0A8M9PH35	InterPro	483
UniProtKB:A0A8M6Z5W1	InterPro	548
UniProtKB:A0A8M9QB09	InterPro	524
UniProtKB:A0A8M9QB24	InterPro	532
UniProtKB:A0A8M9PU99	InterPro	473
UniProtKB:A0AB32TIG8	InterPro	513
UniProtKB:A0AB32TIG9	InterPro	512
UniProtKB:A0AB32TJR8	InterPro	554
UniProtKB:A0AB32TJT4	InterPro	493
UniProtKB:A0AB32TJW4	InterPro	557
UniProtKB:A0AB32TJY0	InterPro	502
UniProtKB:A0AB32TL42	InterPro	552
UniProtKB:A0AB32TL58	InterPro	492
UniProtKB:A0AB32TLI9	InterPro	506
UniProtKB:A0AB32TLK2	InterPro	547
UniProtKB:A0AB32TLM1	InterPro	486
UniProtKB:A0AB32TM51	InterPro	544
UniProtKB:A0AB32TM66	InterPro	482
UniProtKB:A0AB32TNN1	InterPro	538
UniProtKB:A0AB32TNP6	InterPro	476
UniProtKB:A0AB32TP15	InterPro	558
UniProtKB:A0AB32TP35	InterPro	503
UniProtKB:A0AB32TPX8	InterPro	532
UniProtKB:A0AB32TQD3	InterPro	528
UniProtKB:A0AB32TQK7	InterPro	534
UniProtKB:A0AB32TQM4	InterPro	472
UniProtKB:A0AB32TQS3	InterPro	548
UniProtKB:A0AB32TQT8	InterPro	487
UniProtKB:A0AB32TS22	InterPro	532

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	celf2-201 (1) Ensembl	Ensembl	1,699 nt	Select Tool ZFIN BLAST
mRNA	celf2-202 (1) Ensembl	Ensembl	1,886 nt	Select Tool ZFIN BLAST
mRNA	celf2-203 (1) Ensembl	Ensembl	1,545 nt	Select Tool ZFIN BLAST
mRNA	celf2-204 (1) Ensembl	Ensembl	3,045 nt	Select Tool ZFIN BLAST
mRNA	celf2-205 (1) Ensembl	Ensembl	1,538 nt	Select Tool ZFIN BLAST
mRNA	celf2-206 (1) Ensembl	Ensembl	1,480 nt	Select Tool ZFIN BLAST
mRNA	celf2-207 (1) Ensembl	Ensembl	1,060 nt	Select Tool ZFIN BLAST
mRNA	celf2-208 (1) Ensembl	Ensembl	1,480 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations