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Phenotype Figure Summary
Marker:
birc5b
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
Nair
et al.
, 2013
Fig. 1
birc5b
p1aiue
blastomere astral microtubule disorganized, abnormal
blastomere astral microtubule organization disrupted, abnormal
blastomere cleavage furrow absent, abnormal
blastomere mitotic spindle disorganized, abnormal
mitotic metaphase chromosome alignment disrupted, abnormal
mitotic sister chromatid segregation disrupted, abnormal
whole organism dead, abnormal
Fig. 2
birc5b
p1aiue
egg activation disrupted, abnormal
meiotic metaphase II chromosome alignment disrupted, abnormal
meiotic sister chromatid cohesion involved in meiosis II disrupted, abnormal
oocyte microtubule cytoskeleton organization disrupted, abnormal
sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation disrupted, abnormal
unfertilized egg meiotic spindle bent, abnormal
unfertilized egg microtubule bundle absent, abnormal
Fig. 5
birc5b
p1aiue
actin cytoskeleton organization disrupted, abnormal
blastomere actin filament branched, abnormal
blastomere aster mislocalised, abnormal
blastomere cortical actin cytoskeleton morphology, abnormal
sperm aster formation disrupted, abnormal
Fig. 7
birc5b
p1aiue
blastomere cortical microtubule cytoskeleton disorganized, abnormal
blastomere P granule decreased size, abnormal
protein-RNA complex assembly disrupted, abnormal
Ko
et al.
, 2011
Fig. 6
WT + MO1-birc5b
head decreased size, abnormal
neuron apoptotic process increased occurrence, abnormal
neuron differentiation disrupted, abnormal
Fig. 9
WT + MO1-birc5b
G1 to G0 transition disrupted, abnormal
head decreased size, abnormal
neuron differentiation disrupted, abnormal
Delvaeye
et al.
, 2009
Fig. 2
WT + MO1-birc5b
brain decreased size, abnormal
head decreased size, abnormal
head motor neuron disorganized, abnormal
sinus venosus decreased functionality, abnormal
sinus venosus increased accumulation blood, abnormal
Fig. 3
la116Tg + MO1-birc5b
, 
y1Tg + MO1-birc5b
aortic arch hypoplastic, abnormal
axial vasculature decreased diameter, abnormal
caudal vein plexus morphology, abnormal
lateral plate mesoderm angioblastic mesenchymal cell cellular motility, abnormal
Fig. 4
WT + MO1-birc5b
erythrocyte differentiation disrupted, abnormal
nucleate erythrocyte decreased amount, abnormal
Fig. 5
WT + MO1-birc5b
atrioventricular valve decreased diameter, abnormal
cardiac ventricle decreased size, abnormal
endocardial ring decreased size, abnormal
Fig. 6
WT + MO1-birc5b
axial vasculature apoptotic, abnormal
caudal vein plexus apoptotic, abnormal
posterior neural tube apoptotic, abnormal
Fig. 7
WT + MO1-birc5b
caudal vein plexus proliferative region decreased functionality, abnormal
cell population proliferation decreased occurrence, abnormal
hemopoiesis decreased occurrence, abnormal
neural tube proliferative region decreased functionality, abnormal
Fig. 8
y1Tg + MO1-birc5b
caudal vein plexus morphology, abnormal
Ma
et al.
, 2009
Fig. 3
WT + MO5-birc5b
embryonic camera-type eye development delayed, abnormal
head development delayed, abnormal
Fig. 4
WT + MO5-birc5b
, 
la781Tg + MO5-birc5b
blood circulation decreased occurrence, abnormal
erythroid lineage cell decreased amount, abnormal
primitive hemopoiesis disrupted, abnormal
Fig. 6
WT + MO5-birc5b
, 
la781Tg + MO5-birc5b
apoptotic process increased occurrence, abnormal
erythroid lineage cell decreased amount, abnormal
intermediate cell mass of mesoderm apoptotic, abnormal
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