Gene

krt18a.1

ID
ZDB-GENE-030411-6
Name
keratin 18a, tandem duplicate 1
Symbol
krt18a.1 Nomenclature History
Previous Names
  • cb83 (1)
  • DreK18 (1)
  • krt18
  • sb:cb83
  • wu:fa13f02
  • wu:fb36b04 (1)
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to have structural molecule activity. Predicted to localize to intermediate filament. Is expressed in several structures, including EVL; cardiovascular system; gall bladder; head; and pronephric duct. Human ortholog(s) of this gene implicated in liver cirrhosis. Orthologous to human KRT18 (keratin 18).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
22 figures from 16 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With krt18a.1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Cirrhosis, cryptogenic 215600
{Cirrhosis, noncryptogenic, susceptibility to} 215600
Associated With krt18a.1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018039 Intermediate filament protein, conserved site
Domain IPR039008 Intermediate filament, rod domain
Family IPR002957 Keratin, type I
Domain Details Per Protein
Protein Length Intermediate filament protein, conserved site Intermediate filament, rod domain Keratin, type I
UniProtKB:B2GQG8 431
UniProtKB:Q7ZTS4 431
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations