ZFIN ID: ZDB-PUB-030304-2
Expression of isotocin-neurophysin mRNA in developing zebrafish
Unger, J.L. and Glasgow, E.
Date: 2003
Source: Gene expression patterns : GEP   3(1): 105-108 (Journal)
Registered Authors: Glasgow, Eric, Unger, Jennifer L.
Keywords: none
MeSH Terms:
  • Amino Acid Sequence
  • Animals
  • Molecular Sequence Data
  • Neurophysins/biosynthesis
  • Neurophysins/genetics*
  • Oxytocin/analogs & derivatives*
  • Oxytocin/biosynthesis
  • Oxytocin/genetics*
  • Phylogeny
  • RNA, Messenger/metabolism*
  • Zebrafish/embryology*
PubMed: 12609611 Full text @ Gene Expr. Patterns
Neurohypophysial peptides are important regulators of homeostasis, reproduction and behavior. We have sequenced a zebrafish cDNA representing isotocin-neurophysin (IT-NP) mRNA. The developmental expression pattern of zebrafish IT-NP mRNA was determined by whole-mount in situ hybridization histochemistry. At 32 h post fertilization (hpf) no IT-NP mRNA is detected. However, by 36 hpf, staining for IT-NP mRNA is detected in a tight bilateral cluster of cells located in the anterior hypothalamus. The IT-NP mRNA expression pattern remains remarkably stable throughout further development at least until 120 hpf.