ZFIN is now using GRCz12tu for Genomic Data
Gene
pmela
- ID
- ZDB-GENE-030131-9818
- Name
- premelanosome protein a
- Symbol
- pmela Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Acts upstream of or within several processes, including amyloid fibril formation; melanocyte differentiation; and melanosome organization. Predicted to be located in membrane. Predicted to be active in melanosome and plasma membrane. Is expressed in several structures, including eye; hypodermis; immature eye; notochord; and pigment cell. Orthologous to human PMEL (premelanosome protein).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 18 figures from 13 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb397 (15 images)
Wild Type Expression Summary
- All Phenotype Data
- 13 figures from 8 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000601 | PKD domain |
| Domain | IPR022409 | PKD/Chitinase domain |
| Domain | IPR046846 | PKAT, KLD domain |
| Domain | IPR059017 | PMEL/NMB, N-terminal domain |
| Family | IPR045219 | PKD- and KLD-Associated Transmembrane |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR035986 | PKD domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Immunoglobulin-like fold | PKAT, KLD domain | PKD- and KLD-Associated Transmembrane | PKD/Chitinase domain | PKD domain | PKD domain superfamily | PMEL/NMB, N-terminal domain |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9QCX8 | InterPro | 803 | |||||||
| UniProtKB:A0A8M9QLH3 | InterPro | 781 | |||||||
| UniProtKB:Q1ECY0 | InterPro | 825 | |||||||
| UniProtKB:A0AC58GPE1 | InterPro | 878 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers