Gene

hspa4b

ID

ZDB-GENE-030131-6018

Name

heat shock protein 4b

Symbol

hspa4b Nomenclature History

Previous Names

hspa4
wu:fi30e11
zgc:55743
zgc:77413

Type

protein_coding_gene

Location

Chr: 14 Mapping Details/Browsers

Description

Predicted to have ATP binding activity. Predicted to localize to cytosol and nucleus. Is expressed in several structures, including gut; head; liver; neural rod; and pectoral fin bud. Human ortholog(s) of this gene implicated in Chagas disease. Orthologous to human HSPA4 (heat shock protein family A (Hsp70) member 4).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

17 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

Thisse Expression Data

MGC:55743 (1 image)
MGC:77413 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With hspa4b Human Ortholog

No data available

Associated With hspa4b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018181	Heat shock protein 70, conserved site
Domain	IPR042052	HSPA4, nucleotide-binding domain
Family	IPR013126	Heat shock protein 70 family
Homologous_superfamily	IPR029047	Heat shock protein 70kD, peptide-binding domain superfamily
Homologous_superfamily	IPR029048	Heat shock protein 70kD, C-terminal domain superfamily
Homologous_superfamily	IPR043129	ATPase, nucleotide binding domain