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ZIRC
ZFIN ID: ZDB-GENE-030131-6018
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Gene Name: heat shock protein 4b
Gene Symbol: hspa4b    Nomenclature History

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Previous Names: hspa4, wu:fi30e11, zgc:55743, zgc:77413

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 14 Mapping Details/Browsers
Description: Predicted to have ATP binding activity. Predicted to localize to the cytosol and nucleus. Human ortholog(s) of this gene implicated in Chagas disease. Is expressed in several structures, including gut; head; liver; neural rod; and pectoral fin bud. Orthologous to human HSPA4 (heat shock protein family A (Hsp70) member 4).
Genome Resources: Alliance (1),  Gene:334086 (1),  Ensembl(GRCz11):ENSDARG00000018989 (1)
GENE EXPRESSION
All Expression Data: 17 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55743]
  1 figure (1 image) from Thisse et al., 2004 [MGC:77413]
  12 figures (12 images) from Rauch et al., 2003 [fb81d05]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Days 7-13 (168.0h-14d, 4.5mm, 8 teeth)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la018884Tg Transgenic Insertion Unknown Unknown DNA
la018885Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa9130 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa18551 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH hspa4b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH hspa4b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Cellular Component cytosol (more)
    GO Terms (all 2)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR013126 (1)
  • InterPro:IPR018181 (1)
  • InterPro:IPR029047 (1)
  • InterPro:IPR029048 (1)
  • InterPro:IPR042052 (1)
  • PROSITE:PS01036 (1)
  • Pfam:PF00012 (1)
    • TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA hspa4b-201 (1)    Ensembl 3010
    Select Tool
    Browsers: UCSC,  NCBI,  Ensembl,  ZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM hspa4b No data available
    MARKER RELATIONSHIPS
    hspa4b Contained in: [BAC] CH211-119P14 (1) (order this)
    hspa4b Encodes: [EST] fb81d05 (1) (order this), fi30e11
    [cDNA] MGC:55743 (1) (order this), MGC:77413 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_199857 (1) 2979 bp
    Select Tool
    Genomic GenBank:BX470157 (1) 201228 bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q6NZU0 (1) 840 aa
    Select Tool
    Sequence Clusters UniGene:77624 (1)
    Sequence Information (all 18)
    ORTHOLOGY for hspa4b ( Chr: 14 )
    CITATIONS (27)