ZFIN is now using GRCz12tu for Genomic Data
Gene
prom1a
- ID
- ZDB-GENE-030131-1577
- Name
- prominin 1a
- Symbol
- prom1a Nomenclature History
- Previous Names
-
- prom1
- proml1
- fb75c01
- wu:fb75c01
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable cholesterol binding activity. Predicted to be located in endoplasmic reticulum; endoplasmic reticulum-Golgi intermediate compartment; and plasma membrane. Predicted to be active in several cellular components, including apical plasma membrane; microvillus; and prominosome. Is expressed in gill; muscle; nervous system; otic vesicle; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in cone-rod dystrophy 12; retinal macular dystrophy 2; and retinitis pigmentosa 41. Orthologous to human PROM1 (prominin 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 13 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| cone-rod dystrophy 12 | Alliance | Cone-rod dystrophy 12 | 612657 |
| retinal macular dystrophy 2 | Alliance | Macular dystrophy, retinal, 2 | 608051 |
| retinitis pigmentosa 41 | Alliance | Retinitis pigmentosa 41 | 612095 |
| Stargardt disease | Alliance | Stargardt disease 4 | 603786 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR008795 | Prominin |
Domain Details Per Protein
| Protein | Additional Resources | Length | Prominin |
|---|---|---|---|
| UniProtKB:A0A8M9PZ24 | InterPro | 871 | |
| UniProtKB:A0A8M9QGA0 | InterPro | 894 | |
| UniProtKB:A0A8M9QKH3 | InterPro | 879 | |
| UniProtKB:A0A8M9QP25 | InterPro | 855 | |
| UniProtKB:A0A8M3AS96 | InterPro | 879 | |
| UniProtKB:Q9W735 | InterPro | 826 | |
| UniProtKB:A0A8M9QGA5 | InterPro | 860 | |
| UniProtKB:A0A8M3AI42 | InterPro | 896 | |
| UniProtKB:A0A0R4IAM7 | InterPro | 862 | |
| UniProtKB:A0A8M9QP21 | InterPro | 893 | |
| UniProtKB:A0A0R4IE66 | InterPro | 856 | |
| UniProtKB:A0A8M9QAU9 | InterPro | 902 | |
| UniProtKB:A0A0R4IHU7 | InterPro | 849 | |
| UniProtKB:H7BWW9 | InterPro | 841 | |
| UniProtKB:A0AB32T1E5 | InterPro | 888 | |
| UniProtKB:A0AB32T288 | InterPro | 865 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| aberrant processed transcript |
prom1a-204
(1)
|
Ensembl | 3,051 nt | ||
| aberrant processed transcript |
prom1a-208
(1)
|
Ensembl | 3,069 nt | ||
| mRNA |
prom1a-201
(1)
|
Ensembl | 5,946 nt | ||
| mRNA |
prom1a-202
(1)
|
Ensembl | 2,948 nt | ||
| mRNA |
prom1a-205
(1)
|
Ensembl | 3,625 nt | ||
| mRNA |
prom1a-206
(1)
|
Ensembl | 2,972 nt | ||
| mRNA |
prom1a-207
(1)
|
Ensembl | 3,616 nt | ||
| ncRNA |
prom1a-002
(1)
|
Ensembl | 516 nt | ||
| ncRNA |
prom1a-004
(1)
|
Ensembl | 2,670 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-prom1a | polyclonal | Rabbit |
|
1 |
Plasmids
No data available
- Genome Browsers