Gene

impdh2

ID
ZDB-GENE-030114-5
Name
IMP (inosine 5'-monophosphate) dehydrogenase 2
Symbol
impdh2 Nomenclature History
Previous Names
  • cb635 (1)
  • wu:fb64g02
  • wu:fc43f09
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to have IMP dehydrogenase activity; metal ion binding activity; and nucleotide binding activity. Involved in circadian rhythm. Predicted to localize to cytoplasm and nucleus. Is expressed in several structures, including digestive system; immature eye; mesoderm; muscle; and nervous system. Orthologous to human IMPDH2 (inosine monophosphate dehydrogenase 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Li et al., 2015
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With impdh2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
[IMPDH2 enzyme activity, variation in] 617995
Associated With impdh2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR015875 IMP dehydrogenase / GMP reductase, conserved site
Domain IPR000644 CBS domain
Domain IPR001093 IMP dehydrogenase/GMP reductase
Family IPR005990 Inosine-5'-monophosphate dehydrogenase
Homologous_superfamily IPR013785 Aldolase-type TIM barrel
Domain Details Per Protein
Protein Length Aldolase-type TIM barrel CBS domain IMP dehydrogenase/GMP reductase IMP dehydrogenase / GMP reductase, conserved site Inosine-5'-monophosphate dehydrogenase
UniProtKB:B0UXP9 514
UniProtKB:Q7ZYW9 514
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations