Gene

utp25

ID

ZDB-GENE-021217-2

Name

UTP25 small subunit processor component

Symbol

utp25 Nomenclature History

Previous Names

chunp6870
def
diexf
dj434o14.5l
fc51g08
fi05f05
lily liver
lly
wu:fc51g08 (1)
wu:fi05f05

Type

protein_coding_gene

Location

Chr: 13 Mapping Details/Browsers

Description

Predicted to enable U3 snoRNA binding activity and rRNA binding activity. Involved in embryonic organ development and protein localization to nucleolus. Acts upstream of or within several processes, including digestive system development; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); and protein destabilization. Located in nucleolus. Is expressed in digestive system and swim bladder. Orthologous to human UTP25 (UTP25 small subunit processome component).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

9 figures from 5 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:63753 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 10 figures from 8 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With utp25 Human Ortholog

No data available

Associated With utp25 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR053939	UTP25, C-terminal domain
Domain	IPR053940	UTP25, NTP hydrolase-like domain
Family	IPR010678	U3 small nucleolar RNA-associated protein 25
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase