ZFIN is now using GRCz12tu for Genomic Data
Gene
sec61a1a
- ID
- ZDB-GENE-020418-2
- Name
- SEC61 translocon subunit alpha 1a
- Symbol
- sec61a1a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Is expressed in several structures, including axis; digestive system; hatching gland; midbrain hindbrain boundary; and polster. Human ortholog(s) of this gene implicated in autosomal dominant tubulointerstitial kidney disease 5; common variable immunodeficiency; and severe congenital neutropenia. Orthologous to human SEC61A1 (SEC61 translocon subunit alpha 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 15 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6907835 (14 images)
Wild Type Expression Summary
- All Phenotype Data
- 15 figures from 6 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant tubulointerstitial kidney disease 5 | Alliance | Tubulointerstitial kidney disease, autosomal dominant, 5 | 617056 |
| Immunodeficiency, common variable, 15 | 620670 | ||
| ?Neutropenia, severe congenital, 11, autosomal dominant | 620674 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
No data available
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
sec61a1-201
(1)
|
Ensembl | 2,586 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers