Gene
cyp1a
- ID
- ZDB-GENE-011219-1
- Name
- cytochrome P450, family 1, subfamily A
- Symbol
- cyp1a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to have monooxygenase activity. Involved in cellular aromatic compound metabolic process; cellular response to organic cyclic compound; and cellular response to xenobiotic stimulus. Predicted to localize to intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including autoimmune hypersensitivity disease (multiple); bone inflammation disease (multiple); gastrointestinal system cancer (multiple); hematologic cancer (multiple); and lung disease (multiple). Is expressed in several structures, including digestive system; pectoral fin bud; pericardial region; tail bud; and vasculature. Orthologous to several human genes including CYP1A1 (cytochrome P450 family 1 subfamily A member 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 121 figures from 59 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7163229 (13 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cytochrome P450 | Cytochrome P450, conserved site | Cytochrome P450, E-class, group I | Cytochrome P450, E-class, group I, CYP1 | Cytochrome P450 superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:Q8UW07
|
519 |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-cyp1a | monoclonal | IgG3 , k | Mouse |
|
Cayman Chemical Company
Biosense Laboratories |
10 | |
| Ab3-cyp1a | monoclonal | IgG | Mouse |
|
Absolute Biotech
|
2 |
Plasmids
No data available