Gene

jag2b

ID
ZDB-GENE-011128-3
Name
jagged canonical Notch ligand 2b
Symbol
jag2b Nomenclature History
Previous Names
  • jag2
  • jagged2
  • serB
  • serrateB
  • unp1068
  • zgc:152855
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to enable Notch binding activity and calcium ion binding activity. Acts upstream of or within animal organ development. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of protein-containing complex. Predicted to be active in plasma membrane. Is expressed in several structures, including anterior neural rod; digestive system; mesoderm; nervous system; and trunk. Orthologous to human JAG2 (jagged canonical Notch ligand 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
41 figures from 28 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
9 figures from 5 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With jag2b Human Ortholog
No data available
Associated With jag2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018097 EGF-like calcium-binding, conserved site
Domain IPR000742 EGF-like domain
Domain IPR001007 VWFC domain
Domain IPR001774 Delta/Serrate/lag-2 (DSL) protein
Domain IPR001881 EGF-like calcium-binding domain
Domain IPR011651 Notch ligand, N-terminal domain
Family IPR026219 Jagged/Serrate protein
Family IPR033108 Protein jagged-1
Homologous_superfamily IPR009030 Growth factor receptor cysteine-rich domain superfamily
PTM IPR000152 EGF-type aspartate/asparagine hydroxylation site
Domain Details Per Protein
Protein Length Delta/Serrate/lag-2 (DSL) protein EGF-like calcium-binding, conserved site EGF-like calcium-binding domain EGF-like domain EGF-type aspartate/asparagine hydroxylation site Growth factor receptor cysteine-rich domain superfamily Jagged/Serrate protein Notch ligand, N-terminal domain Protein jagged-1 VWFC domain
UniProtKB:Q5TZK7 1216
UniProtKB:Q9YHU2 1254
UniProtKB:A0A2R8QT22 1216
UniProtKB:Q5TZK8 1254
UniProtKB:B3DKL2 1254
UniProtKB:A0A0R4IAF3 1254
UniProtKB:Q90Y55 1216
UniProtKB:Q90Y56 1254
UniProtKB:Q0P4F9 139
Transcripts
Genome Browsers
Interactions and Pathways
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations