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ZIRC
ZFIN ID: ZDB-GENE-010426-3
Gene Name: cryptochrome circadian regulator 1b
Gene Symbol: cry1b    Nomenclature History

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Previous Names: cry1ab, cry1b, zcry1b (1), fi26e03, wu:fi26e03 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 18 Mapping Details/Browsers
Description: Involved in negative regulation of transcription, DNA-templated. Localizes to the nucleus. Human ortholog(s) of this gene implicated in advanced sleep phase syndrome. Is expressed in brain; eye; inner ear; liver; and ovary. Orthologous to human CRY1 (cryptochrome circadian regulator 1).
Genome Resources: Alliance (1),  Gene:554836 (1),  Ensembl(GRCz11):ENSDARG00000011583 (2)
GENE EXPRESSION
All Expression Data: 11 figures from 8 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55968]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hu892 Point Mutation Unknown Premature Stop ENU
hu893 Point Mutation Unknown Splice Site ENU
la020278Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36600 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH cry1b HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    {Delayed sleep phase disorder, susceptibility to} 614163
    DISEASE ASSOCIATED WITH cry1b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of transcription, DNA-templated (more)
    Cellular Component nucleus (more)
    GO Terms (all 3)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cry1ab-201 (1)    Ensembl 3019
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-cry1ab polyclonal Rabbit 1
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cry1b No data available
    MARKER RELATIONSHIPS
    cry1b Contained in: [BAC] CH73-211L16 (1) (order this), DKEY-174I19 (1) (order this)
    cry1b Encodes: [EST] fi26e03 (1)
    [cDNA] MGC:55968 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131790 (1) 3006 bp
    Genomic GenBank:BX571976 183462 bp
    Select Tool
    Polypeptide UniProtKB:F1R1X1 (1) 606 aa
    Sequence Clusters UniGene:158985 (1)
    Sequence Information (all 19)
    ORTHOLOGY for cry1b ( Chr: 18 )
    CITATIONS (60)