Gene
cry1b
- ID
- ZDB-GENE-010426-3
- Name
- cryptochrome circadian regulator 1b
- Symbol
- cry1b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to enable DNA binding activity and FAD binding activity. Acts upstream of or within negative regulation of DNA-templated transcription. Located in nucleus. Is expressed in brain; eye; inner ear; liver; and ovary. Human ortholog(s) of this gene implicated in delayed sleep phase syndrome. Orthologous to human CRY1 (cryptochrome circadian regulator 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 15 figures from 11 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55968 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| {Delayed sleep phase disorder, susceptibility to} | 614163 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR005101 | Cryptochrome/DNA photolyase, FAD-binding domain |
| Domain | IPR006050 | DNA photolyase, N-terminal |
| Family | IPR002081 | Cryptochrome/DNA photolyase class 1 |
| Homologous_superfamily | IPR014729 | Rossmann-like alpha/beta/alpha sandwich fold |
| Homologous_superfamily | IPR036134 | Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily |
| Homologous_superfamily | IPR036155 | Cryptochrome/photolyase, N-terminal domain superfamily |
Domain Details Per Protein
| Protein | Length | Cryptochrome/DNA photolyase class 1 | Cryptochrome/DNA photolyase, FAD-binding domain | Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily | Cryptochrome/photolyase, N-terminal domain superfamily | DNA photolyase, N-terminal | Rossmann-like alpha/beta/alpha sandwich fold |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q7ZU27
|
606 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cry1ab-201
(1)
|
Ensembl | 3,019 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-cry1ab | polyclonal | Rabbit |
|
1 |
Plasmids
No data available