ZFIN ID: ZDB-GENE-001228-2
Gene Name: sphingosine-1-phosphate receptor 1
Gene Symbol: s1pr1    Nomenclature History

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Previous Names: s1p1, edg1 (1), etID43307.22 (1), wu:fb98f05 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 22 Mapping Details/Browsers
Description: Exhibits lysophosphatidic acid receptor activity. Involved in several processes, including ameboidal-type cell migration; circulatory system development; and regulation of blood vessel remodeling. Predicted to localize to cytoplasm and intrinsic component of plasma membrane. Is expressed in several structures, including cardiovascular system; fin bud; nervous system; neural tube; and pleuroperitoneal region. Orthologous to human S1PR1 (sphingosine-1-phosphate receptor 1).
Genome Resources: Alliance (1),  Gene:64617 (1),  Ensembl(GRCz11):ENSDARG00000042690 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ko311 Small Deletion Unknown Unknown TALEN
sa29749 Point Mutation Unknown Splice Site ENU
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
CRISPR1-s1pr1
1
MO1-s1pr1 N/A 1
MO2-s1pr1 N/A 4
MO3-s1pr1 N/A 1
TALEN1-s1pr1 2
DISEASE ASSOCIATED WITH s1pr1 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH s1pr1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process cell migration involved in gastrulation (more)
Cellular Component integral component of membrane (more)
Molecular Function lysophosphatidic acid receptor activity (more)
GO Terms (all 23)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA s1pr1-201 (1)    Ensembl 2352
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM s1pr1 No data available
MARKER RELATIONSHIPS
s1pr1 Contained in: [BAC] DKEY-192M14 (1) (order this)
s1pr1 Encodes: [EST] fb98f05 (1)
[cDNA] MGC:86575 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_131691 (1) 2382 nt
Genomic GenBank:BX908392 (1) 179577 nt
Select Tool
Polypeptide UniProtKB:Q1LV63 (1) 362 aa
Sequence Information (all 16)
ORTHOLOGY for s1pr1 ( Chr: 22 )
CITATIONS (45)