Gene

s1pr1

ID
ZDB-GENE-001228-2
Name
sphingosine-1-phosphate receptor 1
Symbol
s1pr1 Nomenclature History
Previous Names
  • s1p1
  • edg1 (1)
  • etID43307.22 (1)
  • wu:fb98f05 (1)
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Exhibits lysophosphatidic acid receptor activity. Involved in several processes, including ameboidal-type cell migration; circulatory system development; and negative regulation of angiogenesis. Predicted to localize to cytoplasm and intrinsic component of plasma membrane. Is expressed in several structures, including cardiovascular system; fin bud; nervous system; neural tube; and pleuroperitoneal region. Orthologous to human S1PR1 (sphingosine-1-phosphate receptor 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 7 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
12 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With s1pr1 Human Ortholog
No data available
Associated With s1pr1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR017452 GPCR, rhodopsin-like, 7TM
Family IPR000276 G protein-coupled receptor, rhodopsin-like
Family IPR000987 EDG-1 sphingosine 1-phosphate receptor
Family IPR004061 Sphingosine 1-phosphate receptor
Domain Details Per Protein
Protein Length EDG-1 sphingosine 1-phosphate receptor GPCR, rhodopsin-like, 7TM G protein-coupled receptor, rhodopsin-like Sphingosine 1-phosphate receptor
UniProtKB:Q1LV63 362
UniProtKB:Q9DDK4 362
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations