ZFIN ID: ZDB-GENE-001207-3
Gene Name: aryl-hydrocarbon receptor nuclear translocator 2
Gene Symbol: arnt2    Nomenclature History

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Previous Names: arnt2X (1), zfARNT2 (1), chunp6921, unm t30256, unm_t30256, zfARNT2a (1), zfARNT2b (1), zfARNT2c (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Exhibits DNA-binding transcription factor activity. Involved in several processes, including animal organ development; neuron differentiation; and response to hypoxia. Predicted to localize to the nucleus. Is expressed in several structures, including gut; hatching gland; mandibular arch skeleton; nervous system; and vasculature. Orthologous to human ARNT2 (aryl hydrocarbon receptor nuclear translocator 2).
Genome Resources: Alliance (1),  Gene:64277 (1),  Ensembl(GRCz11):ENSDARG00000103697 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi1715Tg Transgenic Insertion 5' UTR Unknown DNA
hi2639cTg Transgenic Insertion 5' UTR Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la025771Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • m1055 Point Mutation Unknown Premature Stop ENU
    sa11162 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa15572 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa20863 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa20864 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa20865 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-arnt2 N/A 1
    MO2-arnt2 N/A 2
    MO3-arnt2 N/A 2
    DISEASE ASSOCIATED WITH arnt2 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    ?Webb-Dattani syndrome 615926
    DISEASE ASSOCIATED WITH arnt2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process response to hypoxia (more)
    Cellular Component nucleus (more)
    Molecular Function DNA-binding transcription factor activity (more)
    GO Terms (all 20)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR000014 PAS domain
    Family IPR001067 Nuclear translocator
    Repeat IPR001610 PAC motif
    Domain IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
    Domain IPR013655 PAS fold-3
    Domain IPR013767 PAS fold
    Homologous_superfamily IPR035965 PAS domain superfamily
    Homologous_superfamily IPR036638 Helix-loop-helix DNA-binding domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA arnt2-201 (1)    Ensembl 2296
    arnt2-204 (1)    Ensembl 6666
    ncRNA arnt2-003 (1)    Ensembl 542
    arnt2-005 (1)    Ensembl 2080
    ottdart00000036705 (1)    Ensembl 1618
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-arnt2 monoclonal IgG1 Mouse Affinity BioReagents (Thermo Fisher Scientific)
    2
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM arnt2 No data available
    MARKER RELATIONSHIPS
    arnt2 Contained in: [BAC] CH73-268O14 (1), DKEY-204O5 (1) (order this)
    arnt2 Encodes: [STS] chunp6921
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131674 (1) 2294 bp
    Genomic GenBank:BX936312 (1) 158510 bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4ILG9 (1) 737 aa
    Sequence Information (all 33)
    ORTHOLOGY for arnt2 ( Chr: 7 )
    CITATIONS (76)