Gene

ybx1

ID
ZDB-GENE-000629-3
Name
Y box binding protein 1
Symbol
ybx1 Nomenclature History
Previous Names
  • yb1
  • hm:zeh0308
  • nsep1 (1)
  • wu:fb01g10 (1)
  • wu:fb08c05 (1)
  • wu:fb16e10
  • wu:fj26c09 (1)
  • Y-box binding protein 1
  • zfY1 (1)
  • zgc:85599
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Enables C5-methylcytidine-containing RNA binding activity; eukaryotic initiation factor 4E binding activity; and methyl-CpG binding activity. Involved in embryonic morphogenesis; mRNA stabilization; and negative regulation of translation. Acts upstream of or within establishment of RNA localization; negative regulation of mRNA processing; and negative regulation of translational initiation. Located in P-body and nucleus. Is expressed in blastoderm; blastodisc; blastomere; eye; and telencephalon. Orthologous to human YBX1 (Y-box binding protein 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
16 figures from 11 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
17 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ybx1 Human Ortholog
No data available
Associated With ybx1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019844 Cold-shock domain, conserved site
Domain IPR002059 Cold-shock protein Csp, DNA-binding
Domain IPR011129 Cold-shock domain
Family IPR050181 Cold shock domain-containing protein
Homologous_superfamily IPR012340 Nucleic acid-binding, OB-fold
Domain Details Per Protein
Protein Length Cold-shock domain Cold-shock domain, conserved site Cold shock domain-containing protein Cold-shock protein Csp, DNA-binding Nucleic acid-binding, OB-fold
UniProtKB:B5DE31 310
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA ybx1-201 (1) Ensembl 1,515 nt
mRNA ybx1-202 (1) Ensembl 1,302 nt
mRNA ybx1-205 (1) Ensembl 1,431 nt
ncRNA ybx1-002 (1) Ensembl 762 nt
ncRNA ybx1-003 (1) Ensembl 686 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab2-ybx1 polyclonal IgG Rabbit
  • IHC
  • WB
Abcam plc
3
Ab3-ybx1 monoclonal IgG , k Mouse
  • IHC
  • WB
Santa Cruz Biotechnology, Inc.
2
Ab4-ybx1 polyclonal Rabbit
  • IHC
Sigma-Aldrich
3
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations