Gene
rplp0
- ID
- ZDB-GENE-000629-1
- Name
- ribosomal protein, large, P0
- Symbol
- rplp0 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable large ribosomal subunit rRNA binding activity. Predicted to be a structural constituent of ribosome. Acts upstream of or within chordate embryonic development. Predicted to be located in cytoplasm; nucleus; and ribosome. Predicted to be part of cytosolic large ribosomal subunit. Is expressed in several structures, including brain; digestive system; eye; otic vesicle; and ovary. Orthologous to several human genes including RPLP0 (ribosomal protein lateral stalk subunit P0).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 20 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56647 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Uechi et al., 2006
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR040637 | Large ribosomal subunit protein uL10-like, insertion domain |
| Family | IPR001790 | Large ribosomal subunit protein uL10 |
| Family | IPR030670 | Large ribosomal subunit protein uL10, eukaryotes |
| Family | IPR050323 | Universal ribosomal protein uL10 |
| Homologous_superfamily | IPR043141 | Large ribosomal subunit protein uL10-like domain superfamily |
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Domain Details Per Protein
| Protein | Additional Resources | Length | Large ribosomal subunit protein uL10 | Large ribosomal subunit protein uL10, eukaryotes | Large ribosomal subunit protein uL10-like domain superfamily | Large ribosomal subunit protein uL10-like, insertion domain | Large ribosomal subunit protein uL10-like, insertion domain superfamily | Universal ribosomal protein uL10 |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q9PV90 | InterPro | 319 | ||||||
| UniProtKB:Q6P5K3 | InterPro | 316 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-160E1 | ZFIN Curated Data | |
| Encodes | EST | fa56b12 | ||
| Encodes | EST | fb04a12 | ||
| Encodes | EST | fb15a08 | ZFIN Curated Data | |
| Encodes | EST | fb19a12 | Rauch et al., 2003 | |
| Encodes | EST | fk48c12 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:56647 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:77791 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:165554 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_131580 (1) | 1105 nt | ||
| Genomic | GenBank:CT573103 (1) | 116681 nt | ||
| Polypeptide | UniProtKB:Q9PV90 (1) | 319 aa |
| Species | Symbol | Chromosome | Accession # | Evidence |
|---|---|---|---|---|
| Human | RPLP0 | 12 | Amino acid sequence comparison (1) |
- Li, Q., Wu, L., Wang, G., Zheng, F., Sun, J., Zhang, Y., Li, Z., Li, L., Sun, B. (2024) Inhibitory Effects of Jiuzao Polysaccharides on Alcoholic Fatty Liver Formation in Zebrafish Larvae and Their Regulatory Impact on Intestinal Microbiota. Foods (Basel, Switzerland). 13(2):
- Ahi, E.P., Brunel, M., Tsakoumis, E., Chen, J., Schmitz, M. (2022) Appetite regulating genes in zebrafish gut; a gene expression study. PLoS One. 17:e0255201
- Maffioli, E., Angiulli, E., Nonnis, S., Grassi Scalvini, F., Negri, A., Tedeschi, G., Arisi, I., Frabetti, F., D'Aniello, S., Alleva, E., Cioni, C., Toni, M. (2022) Brain Proteome and Behavioural Analysis in Wild Type, BDNF+/- and BDNF-/- Adult Zebrafish (Danio rerio) Exposed to Two Different Temperatures. International Journal of Molecular Sciences. 23(10)
- Sojan, J.M., Raman, R., Muller, M., Carnevali, O., Renn, J. (2022) Probiotics Enhance Bone Growth and Rescue BMP Inhibition: New Transgenic Zebrafish Lines to Study Bone Health. International Journal of Molecular Sciences. 23(9)
- Tsakoumis, E., Ahi, E.P., Schmitz, M. (2022) Impaired leptin signaling causes subfertility in female zebrafish. Molecular and Cellular Endocrinology. 546:111595
- Lanes, C.F.C., Pedron, F.A., Bergamin, G.T., Bitencourt, A.L., Dorneles, B.E.R., Villanova, J.C.V., Dias, K.C., Riolo, K., Oliva, S., Savastano, D., Giannetto, A. (2021) Black Soldier Fly (Hermetia illucens) Larvae and Prepupae Defatted Meals in Diets for Zebrafish (Danio rerio). Animals : an open access journal from MDPI. 11(3):
- Pessina, A., Di Vincenzo, M., Maradonna, F., Marchegiani, F., Olivieri, F., Randazzo, B., Gioacchini, G., Carnevali, O. (2021) Polydatin Beneficial Effects in Zebrafish Larvae Undergoing Multiple Stress Types. International Journal of Environmental Research and Public Health. 18(3):
- Delaney, P., Ramdas Nair, A., Palmer, C., Khan, N., Sadler, K.C. (2020) Arsenic induced redox imbalance triggers the unfolded protein response in the liver of zebrafish. Toxicology and applied pharmacology. 409:115307
- Kim, J.E., Min, S.K., Hong, J.M., Kim, K.H., Han, S.J., Yim, J.H., Park, H., Kim, I.C. (2020) Anti-inflammatory effects of methanol extracts from the Antarctic lichen, Amandinea sp. in LPS-stimulated raw 264.7 macrophages and zebrafish. Fish & shellfish immunology. 107(Pt A):301-308
- Liu, Y.S., Yuan, M.H., Zhang, C.Y., Liu, H.M., Liu, J.R., Wei, A.L., Ye, Q., Zeng, B., Li, M.F., Guo, Y.P., Guo, L. (2020) Puerariae Lobatae radix flavonoids and puerarin alleviate alcoholic liver injury in zebrafish by regulating alcohol and lipid metabolism. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 134:111121
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