Gene

pbx3b

ID
ZDB-GENE-000405-3
Name
pre-B-cell leukemia homeobox 3b
Symbol
pbx3b Nomenclature History
Previous Names
  • pbx3.1 (1)
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in animal organ development; neuron development; and regulation of transcription by RNA polymerase II. Predicted to localize to nuclear chromatin. Is expressed in brain; eye; and telencephalon. Orthologous to human PBX3 (PBX homeobox 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Farr et al., 2018
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pbx3b Human Ortholog
No data available
Associated With pbx3b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeodomain
Domain IPR005542 PBX, PBC domain
Domain IPR008422 KN homeodomain
Family IPR050224 Three Amino acid Loop Extension (TALE) homeobox
Homologous_superfamily IPR009057 Homedomain-like superfamily
Domain Details Per Protein
Protein Length Homedomain-like superfamily Homeobox, conserved site Homeodomain KN homeodomain PBX, PBC domain Three Amino acid Loop Extension (TALE) homeobox
UniProtKB:A0A8M3BBW5 388
UniProtKB:A0A8M3AVA6 459
UniProtKB:A0A8M6Z257 382
UniProtKB:Q9I9B5 350
UniProtKB:A0A8M3B234 461
UniProtKB:A4UU10 386
UniProtKB:A0A8M3AVA3 362
UniProtKB:B0V334 376
UniProtKB:A0A8M3B506 469
UniProtKB:A0A8M3AV99 471
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-pbx polyclonal Rabbit
  • WB
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations