Gene
igf2bp3
- ID
- ZDB-GENE-000308-1
- Name
- insulin-like growth factor 2 mRNA binding protein 3
- Symbol
- igf2bp3 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Enables mRNA 3'-UTR binding activity. Acts upstream of or within several processes, including germ cell migration; regulation of embryonic development; and sex determination. Predicted to be located in P-body and cytoplasmic stress granule. Predicted to be active in cytosol and nucleus. Is expressed in female organism; male organism; oocyte stage I; oocyte stage IV; and oocyte stage V. Orthologous to human IGF2BP3 (insulin like growth factor 2 mRNA binding protein 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000504 | RNA recognition motif domain |
| Domain | IPR004087 | K Homology domain |
| Domain | IPR004088 | K Homology domain, type 1 |
| Homologous_superfamily | IPR012677 | Nucleotide-binding alpha-beta plait domain superfamily |
| Homologous_superfamily | IPR035979 | RNA-binding domain superfamily |
| Homologous_superfamily | IPR036612 | K Homology domain, type 1 superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | K Homology domain | K Homology domain, type 1 | K Homology domain, type 1 superfamily | Nucleotide-binding alpha-beta plait domain superfamily | RNA-binding domain superfamily | RNA recognition motif domain |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A0R4IYT0 | InterPro | 607 | ||||||
| UniProtKB:B2GT58 | InterPro | 582 | ||||||
| UniProtKB:A0A8M9P1P8 | InterPro | 322 | ||||||
| UniProtKB:Q9PW80 | InterPro | 582 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| aberrant processed transcript |
igf2bp3-202
(1)
|
Ensembl | 852 nt | ||
| mRNA |
igf2bp3-201
(1)
|
Ensembl | 4,599 nt | ||
| mRNA |
igf2bp3-203
(1)
|
Ensembl | 6,175 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-igf2bp3 | polyclonal | Mouse |
|
2 |
Plasmids
No data available