Gene

igf2bp3

ID

ZDB-GENE-000308-1

Name

insulin-like growth factor 2 mRNA binding protein 3

Symbol

igf2bp3 Nomenclature History

Previous Names

dvr1rbp
IMP3 (1)
Vg1 RBP (1)
zVg1RBP
wu:fb79c12 (1)
wu:fe06h09

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Description

Exhibits mRNA 3'-UTR binding activity. Predicted to be involved in mRNA transport and regulation of translation. Predicted to localize to cytoplasm and nucleus. Is expressed in oocyte stage I and oocyte stage V. Orthologous to human IGF2BP3 (insulin like growth factor 2 mRNA binding protein 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 5 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 9 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With igf2bp3 Human Ortholog

No data available

Associated With igf2bp3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000504	RNA recognition motif domain
Domain	IPR004087	K Homology domain
Domain	IPR004088	K Homology domain, type 1
Homologous_superfamily	IPR012677	Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily	IPR035979	RNA-binding domain superfamily
Homologous_superfamily	IPR036612	K Homology domain, type 1 superfamily

Domain Details Per Protein

Protein	Length	K Homology domain	K Homology domain, type 1	K Homology domain, type 1 superfamily	Nucleotide-binding alpha-beta plait domain superfamily	RNA-binding domain superfamily	RNA recognition motif domain
UniProtKB:A0A0R4IYT0 InterPro	607
UniProtKB:B2GT58 InterPro	582
UniProtKB:A0A8M9P1P8 InterPro	322
UniProtKB:Q9PW80 InterPro	582

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
aberrant processed transcript	igf2bp3-202 (1) Ensembl	Ensembl	852 nt	Select Tool
mRNA	igf2bp3-201 (1) Ensembl	Ensembl	4,599 nt	Select Tool
mRNA	igf2bp3-203 (1) Ensembl	Ensembl	6,175 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab1-igf2bp3	polyclonal	igf2bp3		Mouse	IHC		2

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations