Gene

igf2bp3

ID
ZDB-GENE-000308-1
Name
insulin-like growth factor 2 mRNA binding protein 3
Symbol
igf2bp3 Nomenclature History
Previous Names
  • dvr1rbp
  • IMP3 (1)
  • Vg1 RBP (1)
  • zVg1RBP
  • wu:fb79c12 (1)
  • wu:fe06h09
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Exhibits mRNA 3'-UTR binding activity. Predicted to be involved in mRNA transport and regulation of translation. Predicted to localize to cytoplasm and nucleus. Is expressed in oocyte stage I and oocyte stage V. Orthologous to human IGF2BP3 (insulin like growth factor 2 mRNA binding protein 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
9 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
hza57Allele with one deletionUnknownFrameshift, Premature StopCRISPR
hza58Allele with one deletionUnknownFrameshift, Premature StopCRISPR
la010361TgTransgenic insertionUnknownUnknownDNA
la010393TgTransgenic insertionUnknownUnknownDNA
la010533TgTransgenic insertionUnknownUnknownDNA
la020659TgTransgenic insertionUnknownUnknownDNA
sa6552Allele with one point mutationUnknownSplice SiteENU
sa36823Allele with one point mutationUnknownPremature StopENU
sa43262Allele with one point mutationUnknownSplice SiteENU
sa45668Allele with one point mutationUnknownPremature StopENU
1 - 10 of 11
Show
Sequence Targeting Reagents
1 - 3 of 3
Show
Human Disease
Associated With igf2bp3 Human Ortholog
No data available
Associated With igf2bp3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000504 RNA recognition motif domain
Domain IPR004087 K Homology domain
Domain IPR004088 K Homology domain, type 1
Homologous_superfamily IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily IPR035979 RNA-binding domain superfamily
1 - 5 of 6 Show all
Domain Details Per Protein
Protein Length K Homology domain K Homology domain, type 1 K Homology domain, type 1 superfamily Nucleotide-binding alpha-beta plait domain superfamily RNA-binding domain superfamily RNA recognition motif domain
UniProtKB:A0A0R4IYT0 607
UniProtKB:B2GT58 582
UniProtKB:A0A8M9P1P8 322
UniProtKB:Q9PW80 582
1 - 4 of 4
Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 19
Type Name Annotation Method Has Havana Data Length (nt) Analysis
aberrant processed transcript igf2bp3-202 (1) Ensembl 852 nt
mRNA igf2bp3-201 (1) Ensembl 4,599 nt
mRNA igf2bp3-203 (1) Ensembl 6,175 nt
1 - 3 of 3
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-igf2bp3 polyclonal Mouse
  • IHC
2
1 - 1 of 1
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-155K24ZFIN Curated Data
EncodesESTfb79c12ZFIN Curated Data
EncodesESTfe06h09
EncodescDNAMGC:56031ZFIN Curated Data
EncodescDNAMGC:192856ZFIN Curated Data
1 - 5 of 5
Show
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanIGF2BP37
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
MouseIgf2bp36
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
Citations
1 - 10 of 20
Show