FIGURE

Figure 12

ID

ZDB-FIG-260530-153

Publication

Liu et al., 2026 - The function of TLR2 and the microbiome in macrophage-dependent dissemination of nontuberculous mycobacterial gut infection

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Figure 12

TLR2 deficiency impairs macrophage motility after robotic Mma20 gut microinjection. (A) Schematic of the experimental workflow. (B) Calculation formulas of track displacement and mean speed. (C) Representative images showing trajectories of macrophages at the gut region in tlr2 wild-type and mutant larvae under CONVD and GF conditions. (D) Track displacement of macrophages. (E) Mean speed of macrophages. The data from GF tlr2^+/+ (n=3) group, GF tlr2^-/- (n=3) group, CONVD tlr2^+/+ (n=3) group and CONVD tlr2^-/- (n=3) group are based on three independent experiments (one larva for each group per independent experiment). Statistical significant difference was determined by one-way ANOVA, red arrows point to the median, ns, non-significant, **, P < 0.01, ***, P < 0.001, ****, P < 0.0001.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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