FIGURE

Fig. 8

ID

ZDB-FIG-260427-97

Publication

Lardennois et al., 2026 - Two distinct modes of Vgll4-mediated Tead regulation control organ size in zebrafish

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Fig. 8

yap1 and vgll4b/l are required for proper formation of the pLLP.

Single plane confocal images showing the amount of EdU-stained nuclei in comparison to cldnb:lynGFP signal in yap1^+/+ (a–a”’), yap1^−/− (b–b”’), vgll4b^+/+;vgll4l^+/+ (c–c”’), and vgll4b^−/−;vgll4l^−/− (d–d”’) embryos at 19 hpf. Quantification of pLLP cell number (e), EdU positive cell number (f), and ratio of EdU positive cell number to total pLLP cell number (g) in each condition (N = 1 independent replicate for yap1, N = 3 independent replicates for vgll4). Data are presented as mean ± SD. Unpaired t-tests (Mann–Whitney) were conducted. Scale bar: 20 μm (a–d”’).

Expression Data

Gene:	EGFP
Fish:	zf106Tg/zf106Tg yap1^fu48/fu48; zf106Tg/zf106Tg vgll4l^fu93/fu93; vgll4b^bns23/bns23; zf106Tg/zf106Tg
Anatomical Term:	posterior lateral line primordium
Stage:	20-25 somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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