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Fig. 4

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ZDB-FIG-260129-24

Publication

Radakovic et al., 2025 - Beyond colonization: Candida albicans exhibits substantial pathogenic potential in cystic fibrosis environments

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Fig. 4

CF-mimicking environment decreases the susceptibility of clinical isolates of C. albicans from CF patients to the antifungal drug nystatin.

a Drug-response heatmap showing the effect of nystatin upon different gas and nutritive conditions on the prevalence of filamentous cells in each clinical CF isolate (average of three independent experiments). b Representative images of the dose-dependent effect of nystatin on cell morphology of isolate CF5a in SCFM2 versus RPMI medium. Dashed arrow indicates yeast-like cells, while arrow indicates filaments. c Gas composition significantly influences filamentation-inhibitory effect of nystatin (proportion of filaments), as assessed in SCFM2 and RPMI medium. One-way ANOVA with the Bonferroni test was used to determine statistical significance between groups. ***, P < 0.001.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ NPJ Biofilms Microbiomes