FIGURE

Figure 7.

ID

ZDB-FIG-251219-54

Publication

Stonkus et al., 2025 - A new role for PHYHD1 and related dioxygenases: demethylation of 2'-O-methylated nucleosides

Other Figures

All Figure Page

Back to All Figure Page

Figure 7.

Relative levels of free 2′-O-methylated nucleosides (Nm) compared with unmodified nucleosides (N) in extracts from WT and phyhd1-KO zebrafish embryos (A) and adult zebrafish (B). Embryos were collected 24 h post-fertilization, and adult zebrafish (five each WT and phyhd1-KO males and three each WT and phyhd1-KO females) were collected 3 months post-fertilization. Data represent means ± SEM from at least three biological replicates. Statistical significance was determined using unpaired two-tailed t-tests with Welch correction; P-values are indicated as follows: ns, P > 0.05; *P ≤ 0.05; **P ≤ 0.01; ***P ≤ 0.001.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	phyhd1^vln31/vln31 (AB)
Observed In:	male organism 2'-O-methylcytidine male organism 2'-O-methylguanosine male organism 2'-O-methylinosine male organism 2'-O-methyluridine male organism cordysinin B whole organism 2'-O-methylcytidine whole organism 2'-O-methylguanosine whole organism 2'-O-methylinosine whole organism 2'-O-methyluridine whole organism cordysinin B
Stage Range:	Prim-5 to Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Nucleic Acids Res.