Fig. 12
- ID
- ZDB-FIG-251208-45
- Publication
- Erradhouani et al., 2025 - A new alternative method using cyp3a65 expression in transgenic zebrafish embryos to assess metabolic endocrine-disrupting chemicals in the intestine
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Representative concentration-responses obtained in EMERGE for metals (A), phthalates (B) and perfluorinated compounds (C). GFP expression in zebrafish embryos exposed to (A) cadmium chloride (CdCl2); (B) di(2-ethylhexyl)phthalate (DEHP); (C) perfluorooctanoic acid (PFOA). * denotes significant differences as compared to control DMSO 0.01 %; Kruskal Wallis test followed by Dunn’s test; P ≤ 0.05 (*), P ≤ 0.01 (**), P ≤ 0.001 (***) and P ≤ 0.0001 (****). Data are represented as violon plot with each point representing fluorescent intensity in individual embryo, expressed as fold GFP intensity above control; solid lines represent the median of each test condition. Outliers (detected with GraphPad Prism: ROUT method with Q = 1 %) were removed. All independent experiments can be found in supplementary material. |