FIGURE

Fig. 3

ID

ZDB-FIG-251129-105

Publication

Dougnon et al., 2025 - Behavioral and molecular insights into anxiety in ube3a and fmr1 zebrafish models of autism spectrum disorders

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Fig. 3

Distances travelled during the light-dark test (LDT) in larval ube3a and fmr1 zebrafish.

(A) Distribution of distance travelled in ube3a WT (N = 12) and mutant (N = 11) larvae during alternating light and dark phases (Left panel). Distance travelled in the light and dark between ube3a WT and mutants; unpaired t tests (Right panel). (B) Distribution of distance travelled in fmr1 WT (N = 12) and mutant (N = 12) larvae during alternating light and dark phases (Left panel). Distance travelled in the light and dark between fmr1 WT and mutants; unpaired t tests (Right panel). D1 First Dark phase; L1 First Light phase; D2 Second Dark phase; L2 Second Light phase; D3 Third Dark phase and L3 Third Light phase. The data are presented as boxplots with whiskers (IQR-based). Exact P values are provided in the Figures.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	fmr1^nii8/nii8 (AB) ube3a^{sa9479/sa9479} (AB)
Condition:	lighting conditions
Observed In:	swimming behavior
Stage:	Days 7-13

Phenotype Detail

Acknowledgments

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