FIGURE

FIGURE 8

ID

ZDB-FIG-251105-50

Publication

Owusu Poku et al., 2025 - Thyroid hormone receptor beta-2 (TRβ2) overexpression modulates photoreceptor phenotype diversity in a ligand-dependent manner

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FIGURE 8

Schematic illustration of proposed Trβ2-mediated photoreceptor transfating and ligand-dependent regulation. (A) Trβ2 promotes lws2 expression in RH2 and SWS1 cones, potentially leading to their transfating into LWS2 photoreceptors. (B) In the absence of ligand (unliganded Trβ2) or reduced ligand, lws2 expression is predominantly enhanced. In contrast, ligand-bound Trβ2 (liganded Trβ2) preferentially upregulates lws1 expression. Figure created with BioRender.com.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cell Dev Biol