FIGURE

FIGURE 5

ID

ZDB-FIG-251105-46

Publication

Owusu Poku et al., 2025 - Thyroid hormone receptor beta-2 (TRβ2) overexpression modulates photoreceptor phenotype diversity in a ligand-dependent manner

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FIGURE 5

Trβ2 upregulation precedes lws1 activation and aligns with lws2 downregulation). (A) RT-qPCR analysis of wildtype and trβ2 GOF transgenic fish in a time-series experiment, treated with 100 nM T3, to assess the temporal dynamics of lws1, lws2, and trβ2 mRNA expression. (B) Line graph showing the kinetics of fold change in lws1, lws2, and trβ2 mRNA expression over time (hours post treatment, hpt). Scatter plots and line graphs represent fold changes in transcript expression (2^-ddCT). Each point in the scatter plot corresponds to a biological replicate (n ≥ 6). P-values were determined by comparing ddCT values across groups using Kruskal–Wallis one-way ANOVA with post hoc Dunn’s correction. Statistical significance is indicated as follows: *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001. WT = wildtype; TG = transgenic overexpressing trβ2.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cell Dev Biol