FIGURE

Fig. 6

ID

ZDB-FIG-250901-33

Publication

Malarz et al., 2025 - Unveiling the role of Ndrg1 gene on the oxidative stress induction behind the anticancer potential of styrylquinazoline derivatives

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Fig. 6

The impact of IS20 on the progression of the cell cycle and related molecules in the K562 (A) and U-251 (B) cells. The chart presents the percentage of cells in the G0/G1, S and the G2/M phases of the cell cycle. The mRNA expression of GADD45 in the cells and immunoblotting results with densitometric analysis of cyclin E1, cdc2 and p21 ^CIP1/WAF1 protein expression after 24-hour treatment with IS20. Results were normalized to the reference gene/protein and are from five independent experiments (n = 5). Immunoblots shown are representative from these independent experiments. The displayed blots were cropped, and the full-length blots are shown in Fig. S6. All presented data were analyzed using a one-way ANOVA with Bonferroni’s post-hoc test: *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 compared to the control.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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