FIGURE

Fig. 5

ID

ZDB-FIG-250728-78

Publication

Gregory-Evans et al., 2025 - Mutation of beta-tubulin 4B gene (TUBB4B) causes autosomal dominant retinitis pigmentosa with sensorineural hearing loss in a multigenerational family

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Fig. 5

Audiograms for affected members of the family. Normal hearing range is highlighted by gray boxes (≤19.9 db HL) and specific family members denoted in the bottom right corner of the plot. (A) Hearing test in proband III-4. The X symbol is data from the left ear and the circle symbol is data from the right ear. Blue traces at age 28 and black traces at age 60 show progression of hearing loss over time. PTA scores are denoted in a corresponding color. (B) Hearing test in son of proband (IV-4). Blue traces at age 16 and black traces at age 22 show progression of hearing loss over time. (C) Hearing test in brother of proband (III-1). Audiogram traces at age 57 show severe hearing loss (PTA highest of all members tested). (D) Hearing test in sister of proband (III-6). Audiogram traces at age 51 correspond to lower hearing loss (PTA 45.0) compared to her two siblings (A and C).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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