FIGURE

Fig. 4

ID
ZDB-FIG-250717-41
Publication
Azhwar et al., 2025 - Loss of factor VIII in zebrafish rebalances antithrombin deficiency but has a limited bleeding diathesis
Other Figures
All Figure Page
Back to All Figure Page
Fig. 4

scRNA-seq analysis of f8 and vwf expression in endothelial cells isolated from kdrl-egfp transgenic zebrafish larvae. (A) UMAP (uniform manifold approximation and projection) projection scRNA-seq data from endothelial cells showing f8 expression localized specifically to the endocardial cluster, marked by a red circle. (B-C) Colocalization analysis of f8 with endocardial endothelial–specific markers gata5 and has2 confirms endothelial-specific expression of f8. The red circle marks the endocardial cluster. (D) Expression pattern of vwf, demonstrating localization in both the endocardial (red circle) and arterial endothelial (black circle) clusters.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Blood Adv