FIGURE

Fig. 8

ID

ZDB-FIG-250611-41

Publication

Nayak et al., 2025 - Therapeutic Potential of Methylindoline Derivative in Ameliorating Cadmium-Induced Nephritis Experimented in Zebrafish Model

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Fig. 8

Effect of IC treatment on pro-inflammatory gene expression and Cd-treated renal tissue morphology. (Cd denotes Cadmium; RIPM denotes Rapamycin; TD denotes tubular degeneration; TDO denotes tubular disorganization; GDO denotes glomerular disorganization; HDTC denotes hyaline degeneration of tubular cells; NDTC denotes nuclear degeneration of tubular cells) (a) H&E staining of adult zebrafish intestine (a.1) Control (a.2) Cd (a.3) RIPM (2.5 Μm) (a.4) Cd+IC (100 µM) (a.5) Cd+IC (150 µM) (b) Gene expression levels of TNF-α (c) IL-1β (d) IL-6 (e) NF-κB. Triplicate experiments were conducted, and the results are represented as mean ± SD. The asterix (*) denotes the significance level compared to the control group. *p < 0.0332, **p < 0.0021, ***p < 0.0002, and ****p < 0.0001.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Biochem. Mol. Toxicol.