FIGURE

Fig. 3

ID

ZDB-FIG-250609-35

Publication

Liu et al., 2025 - Knockout of bcas3 gene causes neurodevelopment defects in zebrafish

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Fig. 3

The locomotor activity of bcas3 KO zebrafish larvae. (A), The SPC frequence of 24 hpf zebrafish. SPC, spontaneous curls. (n = 10, per group). (B-D), The basic movement of zebrafish under light condition. (B), Representative image of trajectory and heat map. Quantitative analysis of distance (C) and average velocity (D) in 6 dpf WT and bcas3^−/− larvae. (n = 22, per group). (E), Graph illustrating the movement distance of 6 dpf zebrafish to alternating light-dark conditions, with periods consisting of 5-minute darkness and 5-minute light. The plot graph represents the movement distance of WT and bcas3^−/− larvae per minute. (n = 23, per group). (F), The average velocity of 6 dpf zebrafish during light-dark conditions with periods consisting of 55-minute darkness and 5-minute light. The plot graph represents the average velocity of WT and bcas3^−/− larvae per minute. (n = 23, per group). Data are shown as mean ± SEM. Unpaired Student’s t-test was used to analyze the SPC frequence, distance and average velocity. Significance levels are denoted as follows: ***P < 0.001

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	bcas3^{hzu305/hzu305} (AB)
Condition:	altered light dark cycle
Observed In:	locomotion swimming behavior
Stage Range:	Prim-5 to Day 6

Phenotype Detail

Acknowledgments

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