Fig. 2
- ID
- ZDB-FIG-250421-116
- Publication
- Zheng et al., 2025 - Phenylthiourea synergistically enhances the hepatotoxicity of bavachalcone by interfering with metabolism in zebrafish: A factor to consider when evaluating toxicity of environmental pollutants using zebrafish models
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Effect of PTU combined with BavaC on the morphology, pathological structure and ultrastructure of zebrafish livers: (A): Zebrafish liver, 2D morphology. (B): Zebrafish liver, 3D morphology. (C): Zebrafish liver area statistics (n = 15). (D): Zebrafish liver fluorescence intensity statistics (n = 15). (E): Zebrafish liver volume statistics (n = 15). (F): Zebrafish liver vesicle area statistics (n = 5). (G): HE-stained pathological tissue sections; black arrows indicate vacuoles. (H): Ultrastructural electron microscopy images of the nucleus (N), mitochondria (M), rough endoplasmic reticulum (RER), lysosome (Ly) and autolysosome (ASS); red arrows indicate diseased mitochondria. *p < 0.05 vs. Con, * *p < 0.01 vs. Con, ##p < 0.01 vs. BavaC 2.5 μM. |