FIGURE

Figure 1

ID

ZDB-FIG-250417-107

Publication

Oyarbide et al., 2025 - Reduced EIF6 dosage attenuates TP53 activation in models of Shwachman-Diamond syndrome

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Figure 1

Eif6 accumulation in patients with SDS and sbds-KO zebrafish.

Western blots showing EIF6 accumulation in SDS lymphoblasts (A), SDS PBMCs (B), and sbds-KO fish from 5 dpf to 10 dpf (C). CTL1, healthy control no. 1. (D) IHC images of Eif6 expression showing accumulation in the liver and digestive tract (DT) of 10 dpf zebrafish. Original magnification, ×40.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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